Dissertations

All Dissertations can be found here.

2024

  • Dr. Marvin Brenner; Biopharmaceutical characterization and formulation development of poorly water-soluble phytochemicals using in vivo predictive biphasic dissolution
  • Dr Florian Pöstges; Polymer-mediated solubility enhancement and supersaturation stabilization using various hydroxypropyl cellulose grades within amorphous solid dispersions

2023

  • Dr. Katharina Dauer; Innovative Pharmaceutical Stabilization and Formulation Techniques for Protein Drugs

2022

  • Dr. Marius Johannes Kreiser; Process models for the continuous manufacturing of tablets via direct compression

  • Dr. Ann-Cathrin Willmann; Particle engineering for high dose dry powder inhalation of itraconazole

  • Dr. Barbara Schönfeld; Vacuum drum drying - a novel technology for enabling formulation principles in the development of oral solid dosage forms

  • Dr. Daniel Lagudka; Eigenschaften agglomerierter alpha-Laktose und deren Einfluss auf die Festigkeit von Tabletten bei der Direkttablettierung 

  • Dr. Alexander Denninger; In vivo Relevant Drug Product Evaluation by Using the Biphasic Dissolution Assay (BiPha+) 

  • Dr. Tim Dominik Lillotte; Novel methods as potential process analytical technologies for monitoring the critical quality attributes of compacts; Focus on density and solid fraction

2021

  • Dr. Bashar Ibraheem; Solubility enhancement via pressure induced plastic powder flow 

  • Dr. Anna Katharina Krome; Dissolution, solubility, and stability enhanced formulation strategies for the novel anti-infective corallopyronin A

  • Dr. Judith Menth; Continuous manufacturing: Twin screw wet granulation combined with a continuous fluid bed dryer

  • Dr. Kristina Elena Steffens; Twin-screw melt granulation as alternative granulation strategy

  • Dr. Dnyaneshwar Kapote; Improving solubility and super saturation of poorly soluble drugs using solid dispersions based on natural polymers and mixtures thereof

  • Dr. Alvaro Lopez Marmol; Supersaturation and solubilization to enhance the oral bioavailability of poorly soluble drug molecules: A mechanistic understanding of their potential and limitations 

  • Dr. Marius Monschke; Development and Characterization of Amorphous Solid Dispersions using pH-dependent soluble Polymers via Hot-Melt Extrusion

2020

  • Dr. Fabian Simons; Modifizierte gastroretentive Wirkstofffreisetzung aus festen Dispersionen auf Basis von Kunststoffmatrices

2019

  • Dr. Kathrin Locher; Innovative tools for formulation performance evaluation

  • Dr. Rachel Evans; Investigation of scale-relevant formulation and process parameters for solid dispersions using simulation and material characterization tools

  • Dr. Esther Sophia Bochmann; Model-based formulation of amorphous solid dispersions made by hot-melt extrusion

  • Dr. Anne Cossé; Development of polymeric implants for the long-term release of proteins

2018

  • Dr. Robert Schmidtke; Dry granulation via roller compaction: Investigation on scale up strategies integrating process parameters and critical material attributes 
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