Publications
All publications can also be found on Prof. Wagner ORCID Page
2024
Appelhaus J., Steffens K. E., Wagner K. G.
Effect of Liquid Load Level and Binder Type on the Tabletability of Mesoporous Silica Based Liquisolids
AAPS PharmSciTech, https://doi.org/10.1208/s12249-024-02958-9
Moreira G. G., Taveira S. F., Martins F. T., Wagner K. G., Marreto R. N.
Multivariate Analysis of Solubility Parameters for Drug-Polymer Miscibility Assessment in Preparing Raloxifene Hydrochloride Amorphous Solid Dispersions
AAPS PharmSciTech, https://doi.org/10.1208/s12249-024-02844-4
Lenhard J., Pöstges F., Wagner K. G., Lunter D. J.
Evaluation of Printability of PVA-Based Tablets from Powder and Assessment of Critical Rheological Parameters
Pharmaceutics, https://doi.org/10.3390/pharmaceutics16040553
Becker T., Heitkötter J., Krome A. K., Schiefer A., Pfarr K., Ehrens K., Grosse M., Sandargo B., Stammberger I., Stadler M., Hübner M. P., Kehraus S., Hoerauf A., Wagner K. G., 2024
Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations
Pharmaceutics, https://doi.org/10.3390/pharmaceutics16030386
Brenner M. B., Wüst M., Frank J., Wagner K. G., 2024
In vivo predictive dissolution of the lipophilic phytochemicals trans-resveratrol, coenzyme Q10 and quercetin
Journal of Drug Delivery Science and Technology, https://doi.org/10.1016/j.jddst.2024.105561
Brenner M. B., Wüst M., Kuentz M., Wagner K. G., 2024
High loading of lipophilic compounds in mesoporous silica for improved solubility and dissolution performance
International Journal of Pharmaceutics, https://doi.org/10.1016/j.ijpharm.2024.123946
2023
Pöstges F., Lenhart J., Stoyanov E., Lunter D. J., Wagner K. G., 2023
Phase homogeneity in ternary amorphous solid dispersions and its impact on solubility, dissolution and supersaturation – Influence of processing and hydroxypropyl cellulose grade
International Journal of Pharmaceutics: X, https://doi.org/10.1016/j.ijpx.2023.100222
Brenner M. B., Flory S., Wüst M., Frank J., Wagner K. G., 2023
Novel Biphasic In Vitro Dissolution Method Correctly Predicts the Oral Bioavailability of Curcumin in Humans
Journal of Agricultural and Food Chemistry, https://doi.org/10.1021/acs.jafc.3c04990
Dauer K., Kayser K., Ellwanger F., Overbeck A., Kwade A., Karbstein H. P., Wagner K. G., 2023
Highly protein-loaded melt extrudates produced by small-scale ram and twin-screw extrusion - evaluation of extrusion process design on protein stability by experimental and numerical approaches
International Journal of Pharmaceutics: X, https://doi.org/10.1016/j.ijpx.2023.100196
Denninger A., Becker T., Westedt U., Wagner K. G., 2023
Advanced In Vivo Prediction by Introducing Biphasic Dissolution Data into PBPK Models
Pharmaceutics, https://doi.org/10.3390/pharmaceutics15071978
Neuwirth M., Kappes S. K., Hartig M. U., Wagner K. G, 2023
Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?
Pharmaceutics, https://doi.org/10.3390/pharmaceutics15030764
Dauer K., Wagner K. G., 2023
Micro-Scale Vacuum Compression Molding as a Predictive Screening Tool of Protein Integrity for Potential Hot-Melt Extrusion Processes
Pharmaceutics, https://doi.org/10.3390/pharmaceutics15030723
Kreiser M. J., Wabel C., Wagner K. G., 2023
Direct Tableting on a Continuous Manufacturing Line—Impact of Mixing Parameters, Material Densities, and Drug Load on Subsequent Process Parameters and Tablet Quality
AAPS PharmSciTech, https://doi.org/10.1208/s12249-023-02525-8
Pöstges F., Kayser K., Appelhaus J., Monschke M., Gütschow M., Steinebach C., Wagner K. G., 2023
Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs,
Pharmaceutics, https://doi.org/10.3390/pharmaceutics15010156
2022
Dauer K., Werner C., Lindenblatt D., Wagner K. G., 2022
Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion
International Journal of Pharmaceutics: X, 10.1016/j.ijpx.2022.100154
Krome A. K., Becker T., Kehraus S., Schiefer A., Gütschow M., Chaverra-Muñoz L., Hüttel S., Jansen R., Stadler M., Ehrens A. et al., 2022
Corallopyronin A: antimicrobial discovery to preclinical development
Natural Product Reports, https://doi.org/10.1039/d2np00012a
Rox K., Becker T., Schiefer A., Grosse M., Ehrens A., Jansen R., Aden T., Kehraus S., König G. M., Krome A. K. et al., 2022
Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus
Pharmaceutics, https://doi.org/10.3390/pharmaceutics15010131
Becker T., Krome A. K., Vahdati S., Schiefer A., Pfarr K., Ehrenz A., Aden T., Grosse M., Jansen R., Alt S., Hesterkamp T., Stadler M., Hübner M. P., Hoerauf A., Wagner K. G., 2022
In Vitro-In Vivo Relationship in Mini-Scale--Enabeling Formulations of Corallopyrinin A
Pharmaceutics, https://doi.org/10.3390/pharmaceutics14081657
Elsayed Y. Y., Kühl T., Dauer K., Sayin A., Wagner K. G., Imhof D., 2022
Bioanalytical Workflow for Qualitative and Quantitative Assessment of Hot-Melt Extruded Lysozyme Formulations
ACS Omega, https://doi.org/10.1021/acsomega.2c03559
Willmann A-C., Berkenfeld K., Faber T., Wachtel H., Boeck G., Wagner K. G., 2022
Itraconazole Nanosuspensions via Dual Centrifugation Media Milling: Impact of Formulation and Process Parameters on Particle Size and Solid-State Conversion as Well as Storage Stability
Pharmaceutics, https://doi.org/10.3390/pharmaceutics14081528
Pöstges, F., Kayser, K., Stoyanov, E., Wagner, K.G., 2022
Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions
International Journal of Pharmaceutics: X, 100115, https://doi.org/10.1016/j.ijpx.2022.100115
Ehrens A., Schiefer A., Krome A. K., Becker T., Rox K., Neufeld H., Aden T., Wagner K. G., Müller R., Grosse M et al, 2022
Pharmacology and early ADMET data of corallopyronin A, a natural product with macrofilaricidal anti-wolbachial activity in filarial nematodes
Front. Trop. Dis., https://doi.org/10.3389/fitd.2022.983107
Schönfeld B. V., Westedt U., Keller B-L., Wagner K. G., 2022
Transformation of Ritonavir Nanocrystal Suspensions into a Redispersible Drug Product via Vacuum Drum Drying
AAPS PharmSciTech, https://doi.org/10.1208/s12249-022-02283-z
Schönfeld B. V.,Westedt U., Wagner K.G., 2022
Compression Modulus and Apparent Density of Polymeric Excipients during Compression—Impact on Tabletability
Pharmaceutics, https://doi.org/10.1208/s12249-021-02140-5
Menth J., Maus M., Wagner K.G., 2022
Assessment of Abrasion-Induced Visual Defects in Twin Screw Wet Granulation Using Wall Friction Measurements
AAPS PharmScieTech, https://doi.org/10.1208/s12249-021-02140-5
Gockel L. M., Pfeifer V., Baltes F., Backmaier R. D., Wagner K. G., Bendas G., Gütschow M., Sosič I., Steineback C., 2022
Design, synthesis, and characterization of PROTACs targeting the androgen receptor in prostate and lung cancer models
Archiv der Pharmazie, https://doi.org/10.1002/ardp.202100467
Kreiser M. J., Wabel C., Wagner K. G., 2022
Impact of Vertical Blender Unit Parameters on Subsequent Process Parameters and Tablet Properties in a Continuous Direct Compression Line
Pharmaceutics, https://doi.org/10.3390/pharmaceutics14020278
Kayser K., Monschke M., Wagner K. G., 2022
ASD Formation Prior to Material Characterization as Key Parameter for Accurate Measurements and Subsequent Process Simulation for Hot-Melt Extrusion
AAPS PharmSciTech, https://doi.org/10.1208/s12249-022-02331-8
2021
Schönfeld B. V., Westedt U., Wagner K. G., 2021
Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying
International Journal of Pharmaceutics: X, https://doi.org/10.1016/j.ijpx.2021.100102
Ibraheem B., Wagner K. G.,
Influence of high pressure compaction on solubility and intrinsic dissolution of ibuprofen binary mixtures employing standard excipients
International Journal of Pharmaceutics: X, https://doi.org/10.1016/j.ijpx.2021.100075
Lilotte T. D., Bebernik P. Keck J., Bommer M., Schröder D., Wagner K. G., 2021
Laser triangulation as a fast and reliable method for determining ribbon solid fraction; focus on accuracy, precision, and measurement time
International Journal of Pharmaceutics, https://doi.org/10.1016/j.ijpharm.2021.121241
Lillotte T. D., Joester M., Fringdt B., Berghaus A., Lammes R. F., Wagner K. G., 2021
UV-VIS spectra as potential process analytical technology (PAT) for measureing the density of compressed materials: Evaluation of the CIELAB color space
International Journal of Pharmaceutics. https://doi.org/10.1016/j.ijpharm.2021.120668
Hirlak O., Dieluweit S., Merkel R., Wagner K. G., 2021
Polymer-mediated drug supersaturation – A spotlight on the interplay between phase-separated amorphous drug colloids and dissolved molecules
Journal of Colloid and Interface Sience, https://doi.org/10.1016/j.jcis.2021.06.089
Lopez Marmol A., Denninger A., Touzet A., Dauer K., Becker T., Pöstges F., Pellequer Y., Lamprecht A., Wagner K. G., 2021
The Relevance of Supersaturation and Solubilization in the Gastrointestinal Tract for oral Bioavailability: An In Vitro vs. In Vivo Approach
International Journal of Pharmaceutics. https://doi.org/10.1016/j.ijpharm.2021.120648
Lillotte T. D., Bebernik P., Wagner K. G., 2021
A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis
Powder Technologie, https://doi.org/10.1016/j.powtec.2020.12.023
Denninger A., Westedt U., Wagner K. G., 2021
Shared IVIVR for Five Commercial Enabling Formulations Using the BiPHa+ Biphasic Dissolution Assay
Pharmaceutics. https://doi.org/10.3390/pharmaceutics13020285
Steffens K. E., Wagner K.G., 2021
Immediate-Release Formulations Produced via Twin-Screw Melt Granulation: Systematic Evaluation of the Addition of Disintegrants
AAPS PharmSciTech, https://doi.org/10.1208/s12249-021-02056-0
Dauer K., Kamm W., Wagner K. G., Pfeiffer-Marek S.,2021
High-Throuput Sceening for Colloidal Stability of Peptide Formulations Using Dynamic and Static Light Scattering
Mol Pharm. https://doi.org/10.1021/acs.molpharmaceut.0c01028
Dauer K., Pfeiffer-Marek S., Wagner K. G., 2021
Microwell Plate-Based Dynamic Light Scattering as a High-Throuput Characterization Tool in Biopharmaceutical Development
Pharmaceutics. https://doi.org/10.3390/pharmaceutics13020172
Schönfeld B., Westedt U., Wagner K. G., 2021
Vacuum drum drying – A novel solvent-evaporation based technology to manufacture amorphous solid dispersions in comparison to spray drying and hot melt extrusion
International Journal of Pharmaceutics, https://doi.org/10.1016/j.ijpharm.2021.120233
Monschke M., Kayser K., Wagner K. G., 2021
Influence of Particle Size and Drug Load on Amorphous Solid Dispersions Containing pH-Dependent Soluble Polymers and the Weak Base Ketoconazole
AAPS PharmSciTech, https://doi.org/10.1208/s12249-020-01914-7
Bachmaier R. D., Monschke M., Faber T., Krome A. K., Pellequer Y., Stoyanov E., Lamprecht A., Wagner K. G., 2021
In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole
International Journal of Pharmaceutics: X, https://doi.org/10.1016/j.ijpx.2021.100076
2020
Steffens K. E., Brenner M. B., Hartig M. U., Monschke M., Wagner K. G., 2020
Melt granulation: A comparison of granules produced via high-shear mixing and twin-screw granulation
Int. Journal of Pharmaceutics. 591, 119941, https://doi.org/10.1016/j.ijpharm.2020.119941
Kapote D. N., Wagner K. G., 2020
Influence of shellac on the improvement of solubility and supersaturation of loratadine amorphous solid dispersion using a new grade of HPMC
Journal of Drug Delivery Science and Technology. 102116, https://doi.org/10.1016/j.jddst.2020.102116
Schiefer A., Hübner M. P., Krome A. K., Lämmer C., Ehrens A., Aden T., Koschel M., Neufeld H., Chaverra-Munoz L., Jansen R., Kehraus S., König G. M., Prgorevc D., Müller R., Stadler M., Hüttel S., Hesterkamp T., Wagner K. G., Pfarr K., Hoerauf A., 2020
Corallopyronin A for short-course anti-wolbachial, microfilaricidal treatment of filarial infections
Plos Neglegted Tropical Diseases, https://doi.org/10.1371/journal.pntd.008930
Krome A. K., Becker T., Kehraus S., Schiefer A., Steinebach C., Aden T., Frohberger, S. J., Kapote D., Jansen R., Chaverra-Munoz L., Hübner M. P., Pfarr K., Hesterkamp T., Stadler M., Gütschow M., König G. M., Hörauf A., Wagner K. G., 2020
Solubility and Stability Enhanced Oral Formulations for the Anti-infective Corallopyronin A
Pharmaceutics, https://doi.org/10.3390/pharmaceutics12111105
Steffens K. E., Wagner K. G., 2020
Compression behaviour of granules produced vis twin-scrw melt granulation: Effect of initial particle size on granulation efficiency
Powder Technology. 374, https://doi.org/10.1016/j.powtec.2020.07.037
Menth J., Maus M., Wagner K. G., 2020
Continious twin screw granulation and fluid bed drying: A mechanistic scaling approach focusing optimal tablet properties
Int. Journal of Pharmaceutics. 586, 119509, https://doi.org/10.1016/j.ijpharm.2020.119509
Steinebach C., Ng Y. L. D., Sosič I., Lee C-S., Chen S., Lindner S., Vu L. P., Bricelj A., Haschemi R., Monschke M. et al., 2020
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders
Chemical Science, https://doi.org/10.1039/D0SC00167H
2019
Monschke M., Kayser K., Wagner, K. G., 2019
Impact of HPMCAS on the Dissolution Performance of Polyvinyl Alcohol Celecoxib Amorphous Solid Dispersions
Pharmaceutics. 12(6), 541. https://doi.org/10.3390/pharmaceutics1206054
Monschke M., Kayser K., Wagner, K. G., 2019
Processing of Polyvinyl Acetate Phthalate in Hot-Melt-Extrusion - Preparation of Amorphous Solid Dispersions
Pharmaceutics. 12(4), 337. https://doi.org/10.3390/pharmaceutics12040337
Denninger A., Weststedt U., Rosenberg J., Wagner K. G., 2019
A Rational Design of a Biphasic Dissolution Setup - Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion
Pharmaceutics. 2020, 12(3), 237 https://doi.org/10.1016/j.ijpharm.2020.119941
Steffens K. E., Wagner K. G., 2019
Dissolution enhancement of carbamazepine using twin-srew melt granulation
European Journal of Pharmaceutics and Biopharmaceutics. https://doi.org/10.1016/j.ejpb.2020.01.006
Hagelstein V., Frindt B., Hucke M., Pieper J., Carstens J., Lammens R. F., Wagner K. G., 2019
Novel ultrasonic in-die measurements during power compression at production relevant speed
Int. Journal of Pharmaceutics. 571, 118761 https://doi.org/10.1016/j.ijpharm.2019.118761
Steffens K. E., Wagner K. G., 2019
Improvement of tablet ability via twin-screw melt granulation: Focus on bindeer distribution
Int. Journal of Pharmaceutics. 570, 118649 https://doi.org/10.1016/j.ijpharm.2019.118649
Steinebach C., Sonic I., Lindner S., Bricelj A., Kohl F., Ng Y. L. D., Monschke M., Wagner K. G., Krönke J., Gütchow, M., 2019
A MedChem toolbox for cereblon-directed PROTACs
MedChemComm, doi:10.1039/C9MD00185A
Evans C. E., Bochmann E. S., Kyeremateng S. O., Grycczke A., Wagner, K. G., 2019
Holistic QbD approach for hot-melt extrusion process design space evaluation: Linking materials science, experimentation and process modeling
Eur. J. Pharm. Biopharm. 141, 149–160. doi:10.1016/j.ejb.2019.05.021
Bochmann, E. S., Neumann, D., Gryczke, A., Wagner, K. G., 2019
Micro-scale solubility assessments and prediction models for active pharmaceutical ingredients in polymeric matrices
Eur. J. Pharm. Biopharm. 141, 111–120. doi:10.1016/j.ejpb.2019.05.012
Monschke M., Wagner, K. G., 2019
Amorphous solid dispersions of weak bases with pH-dependent soluble polymers to overcome limited bioavailability due to gastric pH variability - An in vitro approach
Int. Journal of Pharmaceutics. 564, 162-170. doi:10.1016/j.ipharm.2019.04.034
Simons J. F., Wagner, K. G., 2019
Modeling, design and manufacture of innovative floating gastroretentive drug delivery systems based on hot-melt extrusion
Eur. J. Pharm. Biopharm. 137, 196-208. doi:10.1016/j.ejpb.2019.02.022
Steinebach C., Kehm H., Lindner S., Vu L. P., Köpff S., Lopez Marmol A., Weiler C., Wagner K. G., Reichenzeller M., Krönke J., Gütschow, M. 2019
PROTAC-mediated crosstalk between E3 ligases.
Chemical Communications. 55, 1821-1824. doi:10.1039/C8CC09541H
Evans C. E., Kyeremateng S. O., Asmus L., Degenhardt M., Rosenberg J., Wagner, K. G., 2019
Development and Performance of Highly Sensitive Model Formulation Based on Torasemide to Enhance Hot-Melt Extrusion Process Understanding and Process Development
AAPS PharmSciTech. 19, 1592-1605. doi:10.1208/s1224.9-018-0970-y
Zecevic D. E., Evans C. E., Paulsen K., Wagner, K. G., 2019
From benchtop to pilot scale-experimental study and computational assessment of a hot-melt extrusion scale up of a solid dispersion of dipyridamole and copovidone
Int. Journal of Pharmaceutics. 537, 132-139. doi:10.1016/j.ijpharm.2017.12.03
2018
Locher K., Borghaedt J. M., Wachtel H., Schaefer K. J., Wagner, K. G., 2018
Mechanistic study on hydrodynamics in the mini-scale biphasic dissolution model and its influence on in vitro dissolution and partitioning
Eur. J. Pharm. Biopharm. 124, 328-338. doi:10.1016/j.ejpb.2018.09.005
Hagelstein V., Gerhart M. and Wagner, K. G., 2018
Tricalcium citrate - a new brittle tableting excipient for direct compression and drygranulation with enormous hardness yield
Drug Development and Industrial Pharmacy. doi:10.1080/03639045.2018.1483389
Bochmann E., Gryczke A., Wagner K. G., 2018
Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation
Pharmaceutics, https://doi.org/10.3390/pharmaceutics10030132
2017
Bochmann, E. S., Steffens K. E., Gryczke, A., Wagner*, K. G., 2017
Numerical simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt viscosity
Eur. J. Pharm. Biopharm. 124, 34-42. doi:10.1016/j.ejpb.20176.12.001
Cossé, A., König, C., Lamprecht, A., Wagner*, K. G., 2017
Hot Melt Extrusion for Sustained Protein Release: Matrix Erosion and In Vitro Release of PLGA-Based Implants.
AAPS PharmSciTech 1–12. doi:10.1208/s12249-016-0548-5
Bochmann, E. S., Üstüner E. E., Gryczke, A., Wagner, K. G., 2017
Predicting melt rheology for hot-melt extrusion by means of simple Tg-measurent
Eur. J. Pharm. Biopharm. 119, 47-55. doi:10.1016/j.ejpb.2017.05.010
Schmidtke R., Schröder D., Menth J., Staab A., Braun M., Wagner, K. G., 2017
Prediction of solid fraction from powder mixtures based on single component compression analysis
Int. Journal of Pharmaceutics. 523, 366.375. doi:10.1016/j.ijpharm.2017.03.054
2016
Locher, K., Borghardt, J. M., Frank, K. J., Kloft, C., Wagner, K. G., 2016
Evolution of a mini-scale biphasic dissolution model: Impact of model parameters on partitioning of dissolved API and modelling of in vivo-relevant kinetics.
Eur. J. Pharm. Biopharm. 105, 166–175. doi:10.1016/j.ejpb.2016.06.008
Gierds J., Wagner, K. G., 2016
HPAPIs in tableting: Perspectives for the effect and processing of highly potent active pharmaceutical ingredients
Pharmazeutische Industrie, Vol 78, issue 8, 2016, 1215-11221
Bochmann, E. S., Neumann, D., Gryczke, A., Wagner, K. G., 2016
Micro-scale prediction method for API-solubility in polymeric matrices and process model for forming amorphous solid dispersion by hot-melt extrusion.
Eur. J. Pharm. Biopharm. 107, 40–48. doi:10.1016/j.ejpb.2016.06.015
Wagner, K. G., 2016
Perorale Retardarzneiformen
PHARMAKON 4, 107–116. doi:10.1691/pn.20160013
before 2016
Zecevic, D. E., Meier, R., Daniels, R., Wagner, K. G., 2014
Site specific solubility improvement using solid dispersions of HPMC-AS/HPC SSL - Mixtures.
Eur. J. Pharm. Biopharm. 87, 264–270. doi:10.1016/j.ejpb.2014.03.018
Frank, K. J., Locher, K., Zecevic, D. E., Fleth, J., Wagner, K. G., 2014
In vivo predictive mini-scale dissolution for weak bases: Advantages of pH-shift in combination with an absorptive compartment.
Eur. J. Pharm. Sci. 61, 32–39. doi:10.1016/j.ejps.2013.12.015
Zecevic, D. E., Wagner, K. G., 2013
Rational development of solid dispersions via hot-melt extrusion using screening, material characterization, and numeric simulation tools.
J. Pharm. Sci. 102, 2297–2310. doi:10.1002/jps.23592
Buske, J., König, C., Bassarab, S., Lamprecht, A., Mühlau, S., Wagner, K. G., 2012
Influence of PEG in PEG-PLGA microspheres on particle properties and protein release.
Eur. J. Pharm. Biopharm. doi:10.1016/j.ejpb.2012.01.009
Heigoldt, U., Sommer, F., Daniels, R., Wagner*, K. G., 2010
Predicting in vivo absorption behavior of oral modified release dosage forms containing pH-dependent poorly soluble drugs using a novel pH-adjusted biphasic in vitro dissolution test.
Eur. J. Pharm. Biopharm. 76, 105–111. doi:10.1016/j.ejpb.2010.05.006
Maus, M., Wagner, K. G., Kornherr, A., Zifferer, G., 2008
Molecular dynamics simulations for drug dosage form development: thermal and solubility characteristics for hot-melt extrusion.
Mol. Simul. 34, 1197–1207. doi:10.1080/08927020802411695
Günther, M., Maus, M., Wagner, K. G., Schmidt, P. C., 2005
Hydrophilic solutes in modified carbon dioxide extraction—prediction of the extractability using molecular dynamic simulation.
Eur. J. Pharm. Sci. 25, 321–329. doi:10.1016/j.ejps.2005.03.007
Wagner, K. G., Maus, M., Kornherr, A., Zifferer, G., 2005
Glass transition temperature of a cationic polymethacrylate dependent on the plasticizer content – Simulation vs. experiment.
Chem. Phys. Lett. 406, 90–94. doi:10.1016/j.cplett.2005.02.095
Gruetzmann, R., Wagner, K. G., 2005
Quantification of the leaching of triethyl citrate/polysorbate 80 mixtures from Eudragit® RS films by differential scanning calorimetry.
Eur. J. Pharm. Biopharm. 60, 159–162. doi:10.1016/j.ejpb.2004.11.004
Wagner, K.G ., Gruetzmann, R., 2005
Anion-induced water flux as drug release mechanism through cationic Eudragit RS 30D film coatings.
AAPS J. 7, E668–E677. doi:10.1208/aapsj070367
Wagner, K. G., Dowe, U., Zadnik, J., 2005
Highly loaded interactive mixtures for dry powder inhalers: Prediction of the adhesion capacity using surface energy and solubility parameters.
Pharm. - Int. J. Pharm. Sci. 60, 339–344.
Jonat, S., Hasenzahl, S., Drechsler, M., Albers, P., Wagner, K. G., Schmidt, P. C., 2004
Investigation of compacted hydrophilic and hydrophobic colloidal silicon dioxides as glidants for pharmaceutical excipients.
Powder Technol. 141, 31–43. doi:10.1016/j.powtec.2004.01.020
Wagner, K. G., Dressler, J. A., 2003
A corn starch/α-lactose monohydrate compound as a directly compressible excipient.
Pharm. Technol. Eur. 15, 33–40.
Wagner, K. G., McGinity, J. W., 2002
Influence of chloride ion exchange on the permeability and drug release of Eudragit RS 30 D films.
J. Controlled Release 82, 385–397. doi:10.1016/S0168-3659(02)00145-1
Dressler, J. A., Wagner, K. G., Wahl, M. A., Schmidt, P. C., 2001
Comparison of incremental and inductive displacement transducers on an eccentric tablet press.
Drugs Made Ger. 44, 70–77.
Rey, H., Wagner, K. G., Wehrle, P., Schmidt, P. C., 2000
Development of matrix-based theophylline sustained-release microtablets.
Drug Dev. Ind. Pharm. 26, 21–26. doi:10.1081/DDC-100100323
Wagner, K. G., Krumme, M., Beckert, T. E., Schmidt, P. C., 2000
Development of disintegrating multiple-unit tablets on a high-speed rotary tablet press.
Eur. J. Pharm. Biopharm. 50, 285–292. doi:10.1016/S0939-6411(00)00078-3
Wagner, K. G., Krumme, M., Schmidt, P. C., 2000
Pellet-containing tablets - Examination of distribution and deformation behaviour.
STP Pharma Sci. 10, 327–334.
Wagner, K. G., Krumme, M., Schmidt, P. C., 1999
Investigation of the pellet-distribution in single tablets via image analysis.
Eur. J. Pharm. Biopharm. 47, 79–85. doi:10.1016/S0939-6411(98)00090-3