Gao S, Sylvester K, Song L, Claff T, Jing L, Woodson M, Weiße RH, Cheng Y, Schäkel L, Petry M, Gütschow M, Schiedel AC, Sträter N, Kang D, Xu S, Toth K, Tavis J, Tollefson AE, Müller CE, Liu X, Zhan P. Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity. J Med Chem. 2022 13:13343-13364.

Bueschbell B, Manga P, Schiedel AC. The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor. Front Mol Biosci. 2022, 12:873777. doi: 10.3389/ fmolb. 2022.873777.

Caniceiro, AB, Büschbell, B, Schiedel, AC, Moreira, IS. Class A and C GPCR dimers in neurodegenerative diseases. Current Neuropharmacology, 2022, 20:2081-2141.

Büschbell B, Manga P, Penner E, Schiedel AC*. Evidence for Protein-Protein Interaction between Dopamine Receptors and the G Protein-Coupled Receptor 143. Int J Mol Sci. 2021, 22, 8328. doi: 10.3390/ijms22158328.

Carlos A.V. Barreto, Salete J. Baptista, Beatriz Büschbell, Pedro Magalhães, António J. Preto, Agostinho Lemos, Nícia Rosário-Ferreira, Anke Schiedel, Miguel Machuqueiro, Rita Melo, Irina S. Moreira. Arrestin and G protein interactions with GPCRs: a structural perspective. Book Chapter in GPCRs as Therapeutic Targets. John Wiley and Sons Ltd 2021 ISBN-13: 9781119564744.

Breidenbach J, Lemke C, Pillaiyar T, Schäkel L, Al Hamwi G, Diett M, Gedschold R, Lopez V, Mirza S, Namasivayam V, Schiedel AC, Sylvester K, Thimm D, Vielmuth C, Vu LP, Zyulina M, Gütschow M, Müller CE, Geiger N, Bodem J. Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors. Angew Chem Int Ed Engl. 2021 doi: 10.1002/anie.202016961.

Danish A, Gedschold R, Hinz S, Schiedel AC, Thimm D, Bedner P, Steinhäuser C, Müller CE. A Cellular Assay for the Identification and Characterization of Connexin Gap Junction Modulators. Int J Mol Sci. 2021; 22.

De Filippo E, Hinz S, Pellizzari V, Deganutti G, El-Tayeb A, Navarro G, Franco R, Moro S, Schiedel AC, Müller CE. A2A and A2B adenosine receptors: The extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine. Biochem Pharmacol. 2020; doi: 10.1016/j.bcp.2019.113718.

Dilruba S, Grondana A, Schiedel AC, Ueno NT, Bartholomeusz C, Cinatl J Jr, McLaughlin KM, Wass MN, Michaelis M, Kalayda GV.  Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian Cancer Cells to Cisplatin. Cells. 2020 9, 515. doi:10.3390/cells9020515

Büschbell B, Barreto CAV, Preto AJ, Schiedel AC, Moreira IS. A Complete Assessment of Dopamine Receptor- Ligand Interactions through Computational Methods. Molecules. 2019 24: doi:10.3390/molecules24071196.

Schiedel AC#, Köse M, Barreto C, Büschbell B, Morra G, Sensoy O, Moreira IS. Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers. Curr Top Med Chem. 2018 18:714-746.

Hinz, S, Navarro, G, Borroto-Escuela, D, Seibt, BF, Ammon, YC,  de Filippo, E, Danish, A, Lacher, SK,   Červinková, B, Rafehi, M, Fuxe, K, Schiedel, AC, Franco, R., Müller, CE. Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors. Oncotarget. 2018; 9:13593-13611.

Jespers W, Schiedel AC, Heitman LH, Cooke RM, Kleene L, van Westen GJP, Gloriam DE, Müller CE, Sotelo E, Gutiérrez-de-Terán H. Structural Mapping of Adenosine Receptor Mutations: Ligand Binding and Signaling Mechanisms. Trends Pharmacol Sci. 2018; 39:75-89.

De Filippo E, Manga P, Schiedel AC*. Identification of Novel G Protein-Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism. Invest Ophthalmol Vis Sci. 2017 58, 3118-3126.

Danish A, Namasivayam V, Schiedel AC, Müller CE. Interaction of Approved Drugs with Synaptic Vesicle Protein 2A. Arch Pharm 2017 350, doi: 10.1002/ardp.201700003.

Abdelrahman A, Namasivayam V, Hinz S, Schiedel AC, Köse M, Burton M, El-Tayeb A, Gillard M, Bajorath J, de Ryck M, Müller CE. Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies.Biochem Pharmacol. 2017 125, 41-54.

De Filippo E, Schiedel AC*, Manga P. Interaction between G Protein-Coupled Receptor 143 and Tyrosinase: Implications for Understanding Ocular Albinism Type 1. J Invest Dermatol. 2017 137, 457-465.

Köse M, Schiedel AC, Bauer AA, Poschenrieder H, Burbiel JC, Akkinepally RR, Stachel HD, Müller CE. Focused screening to identify new adenosine kinase inhibitors. Bioorg Med Chem. 2016 24, 5127-5133.

De Filippo, E, Namasivayam V, Zappe L, El-Tayeb A, Schiedel AC, Müller CE. Role of extracellular cysteine residues in the adenosine A2A receptor. Purinergic Signal. 2016 12, 313-29.

Alnouri MW, Jepards S, Casari A, Schiedel AC, Hinz S, Müller CE. Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors. Purinergic Signal. 2015 11, 389-407.

Thimm D, Schiedel AC, Peti-Peterdi J, Kishore BK, Müller CE. The nucleobase adenine as a signalling molecule in the kidney. Acta Physiol (Oxf). 2015, 213, 808-818.

Müller CE, Schiedel AC, Zimmermann H. PURINES 2014: nucleotides, nucleosides and nucleobases - international conference on signalling, drugs and targets. Purinergic Signal. 2014 10, 651-665

Kishore, B., Zhang, Y., Gevorgyan, H., Kohan, D., Schiedel, A., Müller, C., Peti-Peterdi, J. Cellular Localization of Adenine Receptors (AdeR) in the Rat Kidney, and their Functional Significance in the Inner Medullary Collecting Duct. Am. J. Physiol. Renal Physiol.2013, 305, F1298-1305

Funke, M., Thimm, D., Schiedel, A.C., Müller, C.E. 8-Benzamidochromen-4-one-2-carboxylic Acids - Potent and Selective GPR35 Receptor Agonists. J. Med. Chem. 2013, 56, 5182-5197

Thimm, D., Knospe, M., Abdelrahman, A., Moutinho, M., Alsdorf, B.B.A., von  Kügelgen, I., Schiedel, A.C.*, Müller, C.E. Characterization of new G protein-coupled adenine receptors in mouse and hamster. Purinergic Signal. 2013, 9, 415-426

Knospe, M., Müller, C.E., Rosa, P., Abdelrahman, A., Thimm, D., Schiedel, A.C.* The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative binding site. Purinergic Signal. 2013, 9, 367-381

Schiedel, A.C., Lacher, S.K., Linnemann, C., Knolle, P.A., Müller, C.E. Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms. Purinergic Signal. 2013, 9, 351-365

Seibt, B.F.,  Schiedel, A.C.#,  Thimm, D., Hinz, S., Sherbiny, F.F., Müller, C.E. The second extracellular loop of GPCRs determines subtype-selectivity and controls efficacy as evidenced by loop exchange studies at A2 adenosine receptors. Biochem. Pharmacol., 2013, 85, 1317–1329.

Thimm, D., Schiedel, A.C.*,  Sherbiny, F.F., Hinz, S., Hochheiser, K., Bertarelli, D. C.G., Maaß, A., Müller, C.E. Ligand-specific binding and activation of the human adenosine A2B receptor., Biochemistry, 2013, 52, 726-740.

Müller, C.E., Schiedel, A.C., and Baqi, Y. Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development. Pharmacology & Therapeutics, 2012, 135, 292-315.

Schiedel, A.C.; Hinz, S.; Thimm, D.; Sherbiny, F.; Borrmann, T.; Maaß, A.; Müller, C.E. The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: role in ligand binding and receptor function. Biochem. Pharmacol. 2011, 82, 389-399.

Drabczyńska, A.; Yuzlenko, O.; Köse, M.; Paskaleva, M.; Schiedel, A.C.; Karolak-Wojciechowska; J.; Handzlik, J.; Karcz, T.; Kuder, K.; Müller, C.E.; Kieć-Kononowicz, K. Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones. Eur. J. Med. Chem. 2011, 46, 3590-607.

Dettmann, S.; Schiedel, A.; Müller, C.E.; Gust, R. 2-Phenyl-1-[4-(2-piperidine-1-yl-ethoxy)benzyl]-1H-benzimidazoles as Ligands for the Estrogen Receptor: Synthesis and Pharmacological Evaluation. Bioorg. Med. Chem. 2010, 18, 4905-4916.

Borrmann, T.; Abdelrahman, A.; Volpini, R.; Lambertucci, C.; Alksnis, E.; Gorzalka, S.; Knospe, M.; Schiedel, A.C.; Cristalli, G.; Müller, C.E. Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J. Med. Chem. 2009, 52, 5974-5989.

Sherbiny, F.F.; Schiedel, A.C.; Maaß, A.; Müller, C.E. Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the beta2-adrenergic receptor and the human adenosine A2A receptor. J. Comput. Aided Mol. Des. 2009, 23, 807-28.

Dyer, J.H.; Maina, A.; Gomez, I.D.; Cadet, M.; Oeljeklaus, S.; Schiedel, A.C. Cloning, expression and purification of an acetoacetyl CoA thiolase from sunflower cotyledon. Int. J. Biol. Sci. 2009, 5, 736-744.
Köse, M.; Schiedel, A.C. Nucleoside/nucleobase transporters - drug targets of the future? Future Med. Chem.  2009, 1, 303-326.

von Kügelgen, I.; Schiedel, A.C; Hoffmann, K.; Alsdorf, B.B.; Abdelrahman, A.; Müller, C.E. Cloning and Functional Expression of a Novel Gi Protein-Coupled Receptor for Adenine from Mouse Brain. Mol. Pharmacol. 2008, 73, 469-477.

Schiedel, A.C.; Meyer, H.; Alsdorf, B.B.A.; Gorzalka, S.; Brüssel, H.; Müller, C.E. [3H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminants in buffer solutions. Purinergic Signalling 2007, 3, 347-358.

Drabczyńska. A.; Müller, C.E.; Karolak-Wojciechowska, J.; Schumacher, B.; Schiedel, A.; Yuzlenko, O.; Kieć-Kononowicz, K. N9-benzyl-substituted 1,3-dimethyl- and 1,3-dipropyl-pyrimido[2,1-f]purinediones: synthesis and structure-activity relationships at adenosine A1 and A2A receptors. Bioorg. Med. Chem. 2007, 15, 5003-5017.

Drabczyńska, A.; Müller, C.E.; Schiedel, A.; Schumacher, B.; Karolak-Wojciechowska, J.; Fruziński, A.; Zobnina, W.; Yuzlenko, O.; Kieć-Kononowicz, K. Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: structure-activity relationships as adenosine A1 and A2A receptor ligands. Bioorg Med Chem. 2007, 15, 6956-6974.

Schiedel, A.C.; Oeljeklaus, S.; Minihan, P.; Dyer, J.H. Cloning, expression, and purification of glyoxysomal 3-oxoacyl-CoA thiolase from sunflower cotyledon. Protein Expr. Purif. 2004, 33, 25-33.

Mayer, T.; Meyer, M.; Janning, A.; Schiedel, A.C. and Barnekow, A. A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts. Oncogene 1999, 18, 689-701.

Schiedel, A.C.; Barnekow, A.; Mayer, T. Nucleotide induced conformation determines posttranslational isoprenylation of the ras related rab6 protein in insect cells. FEBS Lett. 1995, 376, 113-119.